Review Article
[Retracted] Therapy Strategy of CD47 in Diffuse Large B-Cell Lymphoma (DLBCL)
Table 1
The comparison of anti-CD47 antibodies for treatment of DLBCL.
| Name | Hu5F9-G4 | TTI-621 | NI-1701 |
| Characteristic | Monoclonal antibody | Fusion protein | Bispecific antibody | Target | CD47 | CD47 SIRPα | CD47 CD19 | Phase | Phase I/II clinical | Phase I clinical | Phase I clinical | IgG subclass | IgG4 | IgG1 | Engineered IgG1 | AEs | Anemia, mg/kg: chills, headache fatigue, fever | Infusion-related reactions, thrombocytopenia, chills, fatigue, anemia, nausea, pyrexia, diarrhea | |
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