Review Article

[Retracted] Therapy Strategy of CD47 in Diffuse Large B-Cell Lymphoma (DLBCL)

Table 1

The comparison of anti-CD47 antibodies for treatment of DLBCL.

NameHu5F9-G4TTI-621NI-1701

CharacteristicMonoclonal antibodyFusion proteinBispecific antibody
TargetCD47CD47 SIRPαCD47 CD19
PhasePhase I/II clinicalPhase I clinicalPhase I clinical
IgG subclassIgG4IgG1Engineered IgG1
AEsAnemia,  mg/kg: chills, headache fatigue, feverInfusion-related reactions, thrombocytopenia, chills, fatigue, anemia, nausea, pyrexia, diarrhea