Research Article
miRNA-576 Alleviates the Malignant Progression of Atherosclerosis through Downregulating KLF5
Figure 5
miRNA-576 downregulated β-catenin and suppressed release of inflammatory factors in RAW264.7 cells through targeting KLF5. (a) Protein level of β-catenin in ox-LDL-treated RAW264.7 cells transfected with miRNA-576 mimics or NC. (b) Relative levels of IL-1, IL-6, and TNF-α in ox-LDL-treated RAW264.7 cells transfected with NC, miRNA-576 inhibitor, or miRNA-576 inhibitor+si-KLF5.
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