Research Article

Cyclin B2 (CCNB2) Stimulates the Proliferation of Triple-Negative Breast Cancer (TNBC) Cells In Vitro and In Vivo

Figure 4

CCNB2 ablation suppressed the proliferation of TNBC cells in vitro. (a) Colony formation assays were performed by the use of MDA-MB-231 and HCC-1937 cells transfected with control or CCNB2 shRNA plasmids, and the number of colony in each group was counted. (b) MTT assay results showed the decrease OD value at 570 nm wavelength following CCNB2 depletion. (c) Ki67 expression levels in MDA-MB-231 cells and HCC-137 cells upon the indicated treatment. (d) PCNA expression levels in MDA-MB-231 cells and HCC-1937 cells upon the indicated treatment. Results are presented as , and .
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