Research Article

Cyclin B2 (CCNB2) Stimulates the Proliferation of Triple-Negative Breast Cancer (TNBC) Cells In Vitro and In Vivo

Figure 5

CCNB2 promotes tumor growth of TNBC cells in mice. (a) MDA-MB-231 cells infected with control or CCNB2 shRNA plasmids were subcutaneously implanted into nude mice. After 14 days, tumors began formation, and the volume of tumor in each group was measured every 3 days. After 29 days, all tumors were isolated, and the growth curves were shown. (b) Immunoblot assays showed the expression levels of CCNB2 in control or CCNB2 depletion tumors from mice. Results are presented as , and . Scale bar indicates 5 mm.
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