Association of Preoperative Serum Levels of CEA and CA15-3 with Molecular Subtypes of Breast Cancer

Table 1

General characteristics of study population.

Characteristics		Percentage (%)
All	961
Age (years)
<50	454	47.24
≥50	507	52.76
Histologic grade
Grade 1	70	8.10
Grade 2	589	68.17
Grade 3	205	23.73
Tumor size (cm)
<2	516	57.40
≥2	383	42.60
Node status
N0	508	55.52
N1	407	44.48
ER
Negative	251	26.12
Positive	710	73.78
PR
Negative	292	30.42
Positive	669	69.58
Her-2
Negative	725	75.44
Positive	236	24.56
Ki67 (%)
<14	257	26.80
≥14	702	73.20
Molecular types
Luminal A	224	23.31
Luminal B1	384	39.96
Luminal B2	127	13.22
Her-2+	109	11.34
Triple-negative	117	12.17
CEA (ng/ml)
<5	913	95.01
≥5	48	4.99
CA153 (U/ml)
<25	907	94.38
≥25	54	5.62
CA125 (U/ml)
<35	906	94.28
≥35	55	5.72

Luminal B1: ER+/PR+, Her-2 negative; Luminal B2: ER+/PR+, Her-2 positive; Her-2+: Her-2 overexpression.