Research Article

Association of Preoperative Serum Levels of CEA and CA15-3 with Molecular Subtypes of Breast Cancer

Table 4

Correlation between serum CA15-3 level and clinicopathological factors.

CharacteristicCA15-3 negative ()CA15-3 positive () value

Age (years)0.4001
 <50432 (95.15)22 (4.85)
 ≥50475 (93.69)32 (6.31)
Histologic grade0.0223
 Grade 169 (98.57)1 (1.43)
 Grade 2562 (95.42)27 (4.58)
 Grade 3187 (91.22)18 (8.78)
Tumor size (cm)<0.0001
 <2503 (97.48)13 (2.52)
 ≥2348 (90.86)35 (9.14)
Node status0.0001
 N0493 (97.05)15 (2.95)
 N1371 (91.15)36 (8.85)
ER0.0036
 Negative227 (90.44)24 (9.56)
 Positive680 (95.77)30 (4.23)
PR0.0056
 Negative266 (91.10)26 (8.90)
 Positive641 (95.81)28 (4.19)
Her20.0729
 Negative690 (95.17)35 (4.83)
 Positive217 (91.95)19 (8.05)
Ki67 (%)0.2050
 <14247 (96.11)10 (3.89)
 ≥14658 (93.73)44 (6.27)

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