Transcriptome-Wide Gene Expression in a Murine Model of Ventilator-Induced Lung Injury

Table 1

GO analysis of the most significant clustering module in PPI networks.

Category	Term	value
GOTERM_BP_DIRECT	GO:0006351~transcription, DNA-templated
GOTERM_BP_DIRECT	GO:0045893~positive regulation of transcription, DNA-templated
GOTERM_BP_DIRECT	GO:0006357~regulation of transcription from RNA polymerase II promoter
GOTERM_BP_DIRECT	GO:0006954~inflammatory response	0.013427
GOTERM_BP_DIRECT	GO:0043066~negative regulation of apoptotic process	0.014684
GOTERM_BP_DIRECT	GO:0035914~skeletal muscle cell differentiation	0.024883
GOTERM_BP_DIRECT	GO:0051091~positive regulation of sequence-specific DNA binding transcription factor activity	0.048278
GOTERM_BP_DIRECT	GO:0006355~regulation of transcription, DNA-templated	0.048792
GOTERM_CC_DIRECT	GO:0005634~nucleus
GOTERM_CC_DIRECT	GO:0005654~nucleoplasm	0.039133
GOTERM_MF_DIRECT	GO:0003700~transcription factor activity, sequence-specific DNA binding
GOTERM_MF_DIRECT	GO:0003677~DNA binding
GOTERM_MF_DIRECT	GO:0000978~RNA polymerase II core promoter proximal region sequence-specific DNA binding	0.001059
GOTERM_MF_DIRECT	GO:0043565~sequence-specific DNA binding	0.002782
GOTERM_MF_DIRECT	GO:0001077~transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	0.009683
GOTERM_MF_DIRECT	GO:0000982~transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	0.014036
GOTERM_MF_DIRECT	GO:0046983~protein dimerization activity	0.015108