Research Article
Transcriptome-Wide Gene Expression in a Murine Model of Ventilator-Induced Lung Injury
Table 3
GO enrichment analysis of hub genes.
| | Category | Term | value |
| | GOTERM_BP_DIRECT | GO:0035914~skeletal muscle cell differentiation | | | GOTERM_BP_DIRECT | GO:0045944~positive regulation of transcription from RNA polymerase II promoter | 0.002266 | | GOTERM_BP_DIRECT | GO:0006351~transcription, DNA-templated | 0.002534 | | GOTERM_BP_DIRECT | GO:0070102~interleukin-6-mediated signaling pathway | 0.00354 | | GOTERM_BP_DIRECT | GO:0043066~negative regulation of apoptotic process | 0.006244 | | GOTERM_BP_DIRECT | GO:0050679~positive regulation of epithelial cell proliferation | 0.018091 | | GOTERM_BP_DIRECT | GO:0006355~regulation of transcription, DNA-templated | 0.034263 | | GOTERM_BP_DIRECT | GO:0042493~response to drug | 0.034428 | | GOTERM_BP_DIRECT | GO:0042593~glucose homeostasis | 0.042752 | | GOTERM_CC_DIRECT | GO:0005654~nucleoplasm | 0.016377 | | GOTERM_CC_DIRECT | GO:0005634~nucleus | 0.02582 | | GOTERM_MF_DIRECT | GO:0005125~cytokine activity | 0.001928 | | GOTERM_MF_DIRECT | GO:0001077~transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 0.004063 | | GOTERM_MF_DIRECT | GO:0000978~RNA polymerase II core promoter proximal region sequence-specific DNA binding | 0.008486 | | GOTERM_MF_DIRECT | GO:0000982~transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding | 0.011174 | | GOTERM_MF_DIRECT | GO:0046983~protein dimerization activity | 0.017511 | | GOTERM_MF_DIRECT | GO:0003700~transcription factor activity, sequence-specific DNA binding | 0.022809 | | GOTERM_MF_DIRECT | GO:0008134~transcription factor binding | 0.039418 | | GOTERM_MF_DIRECT | GO:0003677~DNA binding | 0.042522 |
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