GABPA Expression in Endometrial Carcinoma: A Prognostic Marker

Table 2

Univariate and multivariate Cox regression analysis of the GABPA expression and overall survival in EC patients.

Variable	Univariable		Multivariable
	HR (95% CI)	value	HR (95% CI)	value
Age (<60 vs ≥60)	1.747 (0.827-3.692)	0.144	—	0.215
Histology (type I vs type II)	2.237 (1.152-4.343)	0.017	—	0.411
Grade (G1-2 vs G3)	2.933 (1.344-6.401)	0.007	2.381 (1.068-5.310)	0.034
Stage (stage I vs stage II-IV))	3.387 (1.935-7.607)	≤0.001	3.033 (1.505-6.123)	0.002
Surgical (open vs mini-invasive)	0.671 (0.313-1.436)	0.304
GABPA (low vs high)	0.487 (0.246-0.966)	0.040	0.491 (0.246-0.977)	0.043

GABPA: GA-binding protein A; EC: endometrial carcinoma; age: age of endometria carcinoma diagnosis; HR: hazard ratio; CI: confidence interval; bold type and () indicate statistical significance.