GABPA Expression in Endometrial Carcinoma: A Prognostic Marker

Table 3

Univariate and multivariate Cox regression analysis of the GABPA expression and disease-free survival in EC patients.

Variable	Univariable		Multivariable
	HR (95% CI)	value	HR (95% CI)	value
Age (<60 vs ≥60)	1.680 (1.017-2.777)	0.043	1.670 (1.011-2.760)	0.045
Histology (type I vs type II)	1.629 (1.024-2.593)	0.039	—	0.416
Grade (G1-2 vs G3)	1.499 (0.952-2.630)	0.081	—	0.332
Stage (stage I vs stage II-IV))	2.281 (1.482-3.511)	≤0.001	2.219 (1.441-3.418)	≤0.001
Surgical (open vs mini-invasive)	1.039 (0.657-1.643)	0.870
GABPA (low vs high)	0.584 (0.375-0.910)	0.018	0.619 (0.397-0.966)	0.045

GABPA: GA-binding protein A; EC: endometrial carcinoma; age: age of endometria carcinoma diagnosis; HR: hazard ratio; CI: confidence interval; bold type and () indicate statistical significance.