Interleukin-18: A Novel Participant in the Occurrence, Development, and Drug Therapy of Obliterative Bronchiolitis Postlung Transplantation

Table 1

Serum cytokines and MMPs of different groups of mouse heterotopic tracheal transplantation model.

	Isograft group ()	Allograft group ()	Allograft+azithromycin group ()	Allograft+tacrolimus group ()	Allograft+tacrolimus+azithromycin group ()	^a	^b	^c	^d
IL-17 (μg/L)						0.0043	0.0531	0.0141	0.0017
IL-18 (μg/L)						0.0051	0.0351	0.0073	0.0036
IFN-r (ng/L)						0.0606	0.1124	0.0783	0.0102
MMP-8 (μg/L)						0.0464	0.0999	0.0567	0.0690
MMP-9 (μg/L)						0.0262	0.0482	0.0404	0.0194

^a: statistical differences between isograft group and allograft group, ^b: statistical differences between allograft group and allograft+azithromycin group, ^c: statistical differences between allograft group and allograft+tacrolimus group, and ^d: statistical differences between allograft group and allograft+tacrolimus+azithromycin group.