Xp11.2 Translocation Renal Cell Carcinoma: Clinical Characteristics and Potential Prognostic Predictors

Table 2

Risk factors for disease progression in patients with Xp11.2 translocation RCC.

	Univariate analysis			Multivariate Cox regression (last step)
	Progression	No progression		HR (95% CI)
Gender, male ()	4/9	8/15	0.673
Age (year)			0.340
Symptomatic patient ()	6/9	5/15	0.113
Right side ()	5/9	4/15	0.157
Tumor size (cm)			0.435
	7/9	8/15	0.231
	4/9	9/15	0.459
	5/9	2/15	0.028
LDH (U/L)			0.227
Hemoglobin (g/L)			0.306
Fbg (g/L)			0.006	5.761 (1.958-16.949)	0.001
Tumor thrombus of IVC	3/9	2/15	0.243
Lymph node metastasis	6/9	5/15	0.113
Distant metastasis	5/9	1/15	0.007
Radical surgery	5/7	11/15	0.926
Additional treatment
Targeted drug only	2/9	0/15
Surgery only	1/9	7/15
Surgery+interleukin-1	3/9	3/15
Surgery+targeted drug	3/9	5/15

NLR: neutrophil-to-lymphocyte ratio; PLR: platelet-to-lymphocyte ratio; CRP/Alb: C-reactive protein/albumin ratio; LDH: lactic dehydrogenase; Fbg: fibrinogen; IVC: inferior vena cava. For patients who had surgical treatment, .