Early Prediction of Disease Progression in Patients with Severe COVID-19 Using C-Reactive Protein to Albumin Ratio

Table 6

Patients’ clinical outcomes and disease severity scores grouped according to the CRP/Alb ratio.

Variable	^aHigh CRP/Alb ratio ()	^bLow CRP/Alb ratio ()	value
Hospital mortality, [%]	29 (20.6%)	5 (1.5%)	<0.001
ICU admission, [%]	35 (24.8%)	5 (1.5%)	<0.001
Invasive mechanical ventilation, [%]	38 (27.0%)	5 (1.5%)	<0.001
Progress to critical COVID-19, [%]	50 (35.5%)	6 (1.9%)	<0.001
Length of hospital stay of survivors, days	40.0 (34.0-47.8)	29.0 (21.0-35.0)	<0.001
SOFA score	3.0 (3.0-4.0)	2.0 (2.0-3.0)	<0.001
CURB-65 score	1.0 (1.0-2.0)	1.0 (0.0-1.0)	<0.001

Data are presented as medians (IQR) and (%). values were calculated by Mann–Whitney test, Chi-square test, or Fisher’s exact test, as appropriate. values indicate differences between the high CRP/Alb ratio group and low CRP/Alb ratio group. Abbreviations: ICU: intensive care unit; CRP: C-reactive protein; Alb: albumin; SOFA score: Sequential Organ Failure Assessment score. ^a. ^b.