Association of Polymorphisms in Vitamin D-Metabolizing Enzymes DHCR7 and CYP2R1 with Cancer Susceptibility: A Systematic Review and Meta-Analysis

Table 4

The results of Begg’s and Egger’s test for the publication bias.

Comparison type	Begg’s test		Egger’s test
	value	value	value	value
CYP2R1 rs10741657 (G/A)
Heterozygote vs. homozygote wild	0	1	-0.7	0.521
Homozygote variant vs. homozygote wild	0.38	0.707	-0.73	0.503
Dominant model	0	1	-0.53	0.627
Recessive model	0	1	-0.29	0.787
Allelic model	0.75	0.452	-0.38	0.722
CYP2R1 rs12794714 (G/A)
Heterozygote vs. homozygote wild	0.34	0.734	0.21	0.851
Homozygote variant vs. homozygote wild	1.02	0.308	-2.84	0.105
Dominant model	0.34	0.734	-0.01	0.994
Recessive model	1.7	0.089	-9.45	0.011
Allelic model	0.34	0.734	-1.12	0.38
CYP2R1 rs2060793 (G/A)
Heterozygote vs. homozygote wild	0	1	NA	NA
Homozygote variant vs. homozygote wild	0	1	NA	NA
Dominant model	0	1	NA	NA
Recessive model	0	1	NA	NA
Allelic model	0	1	NA	NA
DHCR7 rs12785878 (T/G)
Heterozygote vs. homozygote wild	0.24	0.806	-1.64	0.2
Homozygote variant vs. homozygote wild	-0.24	1	-1.76	0.177
Dominant model	-0.24	1	-1.74	0.18
Recessive model	0.24	0.806	-1.15	0.332
Allelic model	0.24	0.806	-1.56	0.217
DHCR7 rs1790349 (A/G)
Heterozygote vs. homozygote wild	0	1	0.18	0.884
Homozygote variant vs. homozygote wild	0	1	0.13	0.92
Dominant model	0	1	-0.44	0.737
Recessive model	0	1	-2.34	0.257
Allelic model	1.04	0.296	-0.9	0.532

Note: the results are in bold if .