Anti-inflammatory Effects of Alcohol Are Associated with JNK-STAT3 Downregulation in an In Vitro Inflammation Model in HepG2 Cells

Figure 1

Schematic timeline of the experimental design is shown (a). Absolute HepG2 cell viability after stimulation with IL-1β (1 ng/ml) and low (LoD, 85 mM)- and high (HiD, 170 mM)-dose EtOH pretreatment for 1 h (acute) or 72 h (prolonged) is represented (b). Longer exposure to EtOH did not affect cell viability. Unstimulated controls (-); IL-1β-stimulated samples (+).

(a)

(b)