Effect of ORF7 of SARS-CoV-2 on the Chemotaxis of Monocytes and Neutrophils In Vitro

Figure 3

Effect of ORF7 on chemotaxis of neutrophils and monocytes. (a–d) Neutrophils were identified as CD11b+ cells and monocytes as CD14+ positive cells (flow cytometry). (g–n) Chemotaxis of monocytes and neutrophils (upper chamber) in response to A549-ORF cells (lower chamber) was examined by staining (Transwell assay). (e, f) Quantitation of chemotaxis results showing increased monocyte chemotaxis and decreased neutrophil chemotaxis (both ).

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