Pericytes of Indirect Contact Coculture Decrease Integrity of Inner Blood-Retina Barrier Model In Vitro by Upgrading MMP-2/9 Activity

Figure 2

RMPs inhibit EC migration in direct contact coculture. (a) Typical pictures of wound-induced migration assay. Wound repair 24 h and 32 h after the mechanical scratch (top, ECs cultured alone; bottom, ECs cocultured with RMPs). The red lines indicate the edges of wounded area. (b) Quantitative analysis of wound repair 24 h and 32 h after making the scratch. Initial wound area at 0 h is defined as 100%. . Analytical data are presented as the . .

(a)

(b)