Pericytes of Indirect Contact Coculture Decrease Integrity of Inner Blood-Retina Barrier Model <i>In Vitro</i> by Upgrading MMP-2/9 Activity

<div>RMPs upgrade expression of MMP-2 and activity of MMP-2/9 of indirect contact coculture. (a) The abundance of MMP-9 and MMP-2 is confirmed via Western blot in model ECs, model DC, and model IDC. (b) MMP-9 and MMP-2 expression measurements are quantified via normalization to <i>β</i>-actin. (c) Activity of MMP-9 and MMP-2 is evaluated by zymography in 3 models. 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Disease Markers

fig4

Figure 4

Figure 4: Pericytes of Indirect Contact Coculture Decrease Integrity of Inner Blood-Retina Barrier Model <i>In Vitro</i> by Upgrading MMP-2/9 Activity 

Disease Markers

Pericytes of Indirect Contact Coculture Decrease Integrity of Inner Blood-Retina Barrier Model In Vitro by Upgrading MMP-2/9 Activity

Figure 4