Identification of Neuropeptides as Potential Crosstalks Linking Down Syndrome and Periodontitis Revealed by Transcriptomic Analyses

Figure 5

Identification of interesting modules in the DS and PD. (a, b) Scale-free ft index for different powers (β) of DS and PD. (c, d) Log-log plot of the whole-network connectivity distribution showing the quality of the relationship between connectivity (k) and P(K) for DS and PD. The -axis shows the logarithm of whole network connectivity, and -axis shows the logarithm of the corresponding frequency distribution. (e, f) Coexpressed modules obtained by average linkage hierarchical clustering of DS and PD. The color row underneath the dendrogram shows the module assignment determined by the Dynamic Tree Cut. (g, h) Bar plot of mean gene significance across modules. The height of the bars equals the mean value of -log10 ( value) across the observations with a given level of Module. By default, the barplot also shows plus/minus one standard error. The function also outputs the value of a Kruskal Wallis test.

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