Identification of Neuropeptides as Potential Crosstalks Linking Down Syndrome and Periodontitis Revealed by Transcriptomic Analyses

Figure 6

(a, b) PPI network for significant modules of DS and PD. The color of the midpoint in the coexpression network represents the difference in intramodular connectivity scores between a gene and other genes. Due to the large number of genes in the turquoise module for PD, we show the top 10 genes in the intramodular connectivity score and the crosstalk gene in the module. The crosstalk gene was trapped in different colored circles in different modules. (c) The function enrichment for the crosstalk genes in the significant module of DS and PD. (d, e) The prediction of common crosstalk gene in the significant module of DS and PD.

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