Upregulated Transcription Factor PITX1 Predicts Poor Prognosis in Kidney Renal Clear Cell Carcinoma-Based Bioinformatic Analysis and Experimental Verification

Figure 1

PITX1 is highly expressed in KIRC. (a) PITX1 expression in pancancers. (b) Unpaired tumor and normal tissues from the TCGA-KIRC dataset (, ). (c) Paired tissues from the TCGA-KIRC dataset (, ). (d) Paired tissues from the GSE16441-KIRC dataset (, ). (e) Paired tissues from the GSE53757-KIRC (, ). (f) PITX1mRNA expression in the Yusenko renal cohort (, ). (g) PITX1 mRNA expression in the Lenburg renal cohort (, ). (h) Relative expression of PITX1 mRNA in KIRC tissues and adjacent nontumor tissues was detected by qRT-PCR ().

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)