Research Article

Upregulated Transcription Factor PITX1 Predicts Poor Prognosis in Kidney Renal Clear Cell Carcinoma-Based Bioinformatic Analysis and Experimental Verification

Table 2

Relationship between PITX1 mRNA expression and clinical characteristics by logistic regression.

CharacteristicsTotal ()Odds ratio (OR) value

Age (>60 vs. ≤60)5391.259 (0.898-1.767)0.182
Gender (male vs. female)5390.826 (0.578-1.178)0.291
Race (white vs. black or African American)5320.795 (0.469-1.337)0.389
Laterality (right vs. left)5380.719 (0.512-1.010)0.058
T stage (T3+T4 vs. T1+T2)5392.354 (1.640-3.398)<0.001
N stage (N1 vs. N0)2572.831 (0.956-10.349)0.079
M stage (M1 vs. M0)5062.939 (1.764-5.039)<0.001
Pathologic stage (stage III+IV vs. stage I+II)5362.775 (1.938-3.999)<0.001
Histologic grade (G3+G4 vs. G1+G2)5312.384 (1.685-3.388)<0.001
Primary therapy outcome (CR+PR vs. PD+SD)1471.115 (0.403-3.243)0.835

Statistical significance .