Research Article
Upregulated Transcription Factor PITX1 Predicts Poor Prognosis in Kidney Renal Clear Cell Carcinoma-Based Bioinformatic Analysis and Experimental Verification
Table 2
Relationship between PITX1 mRNA expression and clinical characteristics by logistic regression.
| Characteristics | Total () | Odds ratio (OR) | value |
| Age (>60 vs. ≤60) | 539 | 1.259 (0.898-1.767) | 0.182 | Gender (male vs. female) | 539 | 0.826 (0.578-1.178) | 0.291 | Race (white vs. black or African American) | 532 | 0.795 (0.469-1.337) | 0.389 | Laterality (right vs. left) | 538 | 0.719 (0.512-1.010) | 0.058 | T stage (T3+T4 vs. T1+T2) | 539 | 2.354 (1.640-3.398) | <0.001 | N stage (N1 vs. N0) | 257 | 2.831 (0.956-10.349) | 0.079 | M stage (M1 vs. M0) | 506 | 2.939 (1.764-5.039) | <0.001 | Pathologic stage (stage III+IV vs. stage I+II) | 536 | 2.775 (1.938-3.999) | <0.001 | Histologic grade (G3+G4 vs. G1+G2) | 531 | 2.384 (1.685-3.388) | <0.001 | Primary therapy outcome (CR+PR vs. PD+SD) | 147 | 1.115 (0.403-3.243) | 0.835 |
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Statistical significance . |