m⁶A RNA Methylation Regulators Elicit Malignant Progression and Predict Clinical Outcome in Hepatocellular Carcinoma

Table 2

Functional enrichment analysis for the prognostic signature.

Category	Term	Description	Count	FDR
GOTERM_BP	GO:0009451	RNA modification	8
GOTERM_BP	GO:0080009	mRNA methylation	5
GOTERM_BP	GO:1903311	Regulation of mRNA metabolic process	8
GOTERM_BP	GO:0006397	mRNA processing	9
GOTERM_BP	GO:0001510	RNA methylation	6
GOTERM_BP	GO:0016070	RNA metabolic process	11
GOTERM_BP	GO:0006396	RNA processing	10
GOTERM_MF	GO:1990247	N6-methyladenosine-containing RNA binding	5
GOTERM_MF	GO:0003723	RNA binding	8
GOTERM_MF	GO:0140098	Catalytic activity, acting on RNA	5
GOTERM_MF	GO:0016422	mRNA (2-O-methyladenosine-N6-)-methyltransferase activity	2
GOTERM_MF	GO:0003729	mRNA binding	4
GOTERM_MF	GO:0035515	Oxidative RNA demethylase activity	2
GOTERM_CC	GO:0036396	RNA N6-methyladenosine methyltransferase complex	6
GOTERM_CC	GO:0016607	Nuclear speck	8
GOTERM_CC	GO:0005654	Nucleoplasm	10
GOTERM_CC	GO:1902494	Catalytic complex	7
Pathway	HSA-72203	Processing of capped intron-containing pre-mRNA	4	0.00017
Pathway	HSA-73943	Reversal of alkylation damage by DNA dioxygenases	2	0.00017

Abbreviations: GOTERM: Gene Ontology term; BP: biological process; MF: molecular function; CC: cellular component.