A Risk Score Model Based on Nine Differentially Methylated mRNAs for Predicting Prognosis of Patients with Clear Cell Renal Cell Carcinoma

Table 5

Significant enriched KEGG pathways.

Name	Size	ES	NES	NOM value	Enriched genes
KEGG cytokine-cytokine receptor interaction	18	0.5690	1.9390	0	IL6, IL1R2, IL2RA, CCL13, IL20RB, CXCL13, CXCR3, IL21R, TNFRSF17, TNFSF14, TNFRSF9, TNFRSF18, INHBE, IFNG, XCL2, LTA, CD27, XCL1
KEGG neuroactive ligand receptor interaction	11	-0.4944	-1.7734	0.0108	GABRB3, CHRM3, VIPR1, GRIK3, PLG, CALCR, GABRQ, AVPR2, TACR1, AGTR1, F2RL3
KEGG toll-like receptor signaling pathway	2	0.8721	1.5058	0.0188	LBP, IL6
KEGG B cell receptor signaling pathway	3	0.7853	1.5119	0.0448	CD79A, CD72, CARD11

ES: enrichment score; NES: normalized enrichment score; NOM value: nominal value; size: the number of genes enriched in one pathway.