Apolipoprotein B/A1 Ratio Is Associated with Severity of Coronary Artery Stenosis in CAD Patients but Not in Non-CAD Patients Undergoing Percutaneous Coronary Intervention

Table 1

Basic characteristics of the patients with CAD and without CAD.

Variables	Whole ()	Non-CAD ()	CAD ()
ApoB/A1	0.65 (0.52-0.80)	0.61 (0.49-0.75)	0.67 (0.53-0.82)	<0.001
Sex (female)	2503 (36)	897 (50.0)	1606 (31.1)	<0.001
Age (year)	62 (54-68)	60 (53-67)	62 (55-69)	<0.001
Heart rate (bmp)	74 (66-82)	74 (66-82)	74 (66-82)	0.466
Hypertension	3881 (55.8)	886 (49.4)	2995 (58.0)	<0.001
Diabetics	1523 (21.9)	243 (13.5)	1280 (24.8)	<0.001
Smoking history	2878 (41.4)	534 (29.7)	2344 (45.4)	<0.001
RDW (%)	12.8 (12.4-13.3)	12.8 (12.4-13.3)	12.9 (12.4-13.3)	0.514
Hct (%)	41.8 (38.9-44.7)	41.5 (38.6-44.5)	41.9 (38.9-44.7)	0.057
TC (mmol/L)	3.77 (3.16-4.46)	3.79 (3.19-4.44)	3.77 (3.15-4.47)	0.528
TG (mmol/L)	1.30 (0.95-1.83)	1.26 (0.93-1.74)	1.32 (0.96-1.85)	0.001
HDL (mmol/L)	0.96 (0.82-1.13)	1.00 (0.85-1.19)	0.94 (0.81-1.11)	<0.001
LDL (mmol/L)	2.12 (1.63-2.7)	2.13 (1.61-2.69)	2.12 (1.63-2.70)	0.860
ApoB (g/L)	0.72 (0.59-0.88)	0.71 (0.57-0.85)	0.73 (0.59-0.88)	<0.001
ApoA1 (g/L)	1.11 (0.99-1.25)	1.16 (1.03-1.29)	1.10 (0.98-1.23)	<0.001
ALT (U/L)	22 (15-33)	19 (14-29)	23 (16-35)	<0.001
GGT (U/L)	22 (15-35)	20 (14-33)	23 (16-35)	<0.001
TBA (μmol/L)	3.7 (2.2-6.0)	4.0 (2.4-6.6)	3.6 (2.2-5.9)	<0.001
Hcy (μmol/L)	16.30 (12.80-22.00)	15.20 (12.20-19.78)	16.70 (13.10-22.80)	<0.001
TnT-hs (ng/mL)	0.01 (0-0.03)	0.01 (0-0.01)	0.01 (0.01-0.06)	<0.001
CK-MB (U/L)	12 (8-17)	11 (8-15)	12 (9-18)	<0.001
NT-pro-BNP (pg/mL)	122.95 (50.48-378.10)	81.55 (37.05-197.30)	144.50 (58.12-481.45)	<0.001
Scr (μmol/L)	62 (53-73)	60 (50-71)	63 (53-74)	<0.001
Cys C (mg/L)	0.83 (0.64-1.08)	0.82 (0.62-1.06)	0.84 (0.65-1.09)	<0.001
HbA1c (%)	5.70 (5.40-6.20)	5.60 (5.30-5.90)	5.70 (5.40-6.30)	<0.001
Hs-CRP (mmol/L)	1.20 (0.55-3.59)	0.87 (0.40-2.06)	1.42 (0.62-4.31)	<0.001
FIB (g/L)	3.00 (2.56-3.53)	2.85 (2.45-3.32)	3.05 (2.61-3.63)	<0.001
INR	1.02 (0.97-1.06)	1.01 (0.96-1.05)	1.02 (0.97-1.07)	<0.001
D-D (mg/L)	0.45 (0.30-0.65)	0.40 (0.30-0.60)	0.49 (0.30-0.70)	<0.001
FT3 (pmol/L)	4.37 (3.79-5.00)	4.44 (3.83-5.12)	4.35 (3.77-4.95)	<0.001
T3 (pmol/L)	1.10 (0.94-1.28)	1.11 (0.96-1.29)	1.09 (0.93-1.27)	0.002
FT4 (pmol/L)	14.6 (12.5-16.9)	14.9 (12.6-17.2)	14.6 (12.4-16.8)	0.004
T4 (pmol/L)	7.47 (6.22-8.89)	7.53 (6.28-8.96)	7.45 (6.2-8.88)	0.218
Aspirin	6765 (97.3)	1725 (96.1)	5040 (97.7)	0.001
P2y12	6740 (96.9)	1713 (95.4)	5027 (97.4)	<0.001
Statin	6729 (96.7)	1696 (94.5)	5033 (97.5)	<0.001
Anticoagulant	163 (2.3)	52 (2.9)	111 (2.2)	0.085
Gensini score	25.00 (8.00-58.00)	5.00 (2.00-8.00)	40.00 (20.00-72.00)	<0.001

Data are presented as the medians (25th, 75th percentiles) or number (%). ApoB/A1, age, heart rate, RDW, Hct, TC, TG, HDL, LDL, ApoB, ApoA1, ALT, GGT, TBA, Hcy, TnT-hs, CK-MB, NT-pro-BNP, Scr, Cys C, HbA1c, Hs-CRP, FIB, INR, D-D, FT3, T3, FT4, T4, and Gensini score were given as medians (25th, 75th percentiles); sex, hypertension, diabetics, smoking history, and usage of aspirin, p2y12, statin, and anticoagulant were given as number (%) (). RDW = red blood cell distribution width; Hct = hematocrit; TC = total cholesterol; TG = triglyceride; HDL = high-density lipoprotein cholesterol; LDL = low-density lipoprotein cholesterol; ApoB = apolipoprotein B; ApoA1 = apolipoprotein A1; ALT = alanine aminotransferase; GGT = gamma-glutamyl transpeptidase; TBA = total bile acids; Hcy = homocysteine; TnT-hs = hypersensitive troponin T; CK-MB = creatine kinase MB; NT-pro-BNP = N-terminal probrain natriuretic peptide; Scr = serum creatinine; Cys C = cystatin C; HbA1c = hemoglobin A1c; Hs-CRP = high-sensitivity C-reactive protein; FIB = fibrinogen; INR = international normalized ratio; D-D = D-dimer; FT3 = free triiodothyronine; T3 = triiodothyronine; FT4 = free thyroxine; T4 = thyroxine; p2y12 = platelet p2y12 antagonist; CAD = coronary artery disease.