Apolipoprotein B/A1 Ratio Is Associated with Severity of Coronary Artery Stenosis in CAD Patients but Not in Non-CAD Patients Undergoing Percutaneous Coronary Intervention

Table 2

Comparison of clinical data between groups in CAD patients with different level of ApoB/A1.

Variables	ApoB/A1-L (0.14-0.57)	ApoB/A1-M (0.57-0.76)	ApoB/A1-H (0.76-2.45)
Sex/female	631 (36.7)	542 (31.5)	433 (25.1)	<0.001
Age (year)	64 (57-71)	62 (55-69)	60 (52-67)	<0.001
Heart rate (bmp)	72 (64-80)	73 (66-81)	75 (67-84)	<0.001
Hypertension	1033 (60.1)	1023 (59.5)	939 (54.5)	0.001
Diabetics	408 (23.7)	414 (24.1)	458 (26.6)	0.112
Smoking history	696 (40.5)	765 (44.5)	883 (51.2)	<0.001
TC (mmol/L)	3.14 (2.73-3.65)	3.77 (3.28-4.30)	4.46 (3.90-5.14)	<0.001
TG (mmol/L)	1.03 (0.79-1.39)	1.33 (1.01-1.87)	1.64 (1.23-2.26)	<0.001
HDL (mmol/L)	1.04 (0.88-1.21)	0.94 (0.80-1.09)	0.88 (0.77-1.02)	<0.001
LDL (mmol/L)	1.54 (1.25-1.89)	2.15 (1.81-2.55)	2.81 (2.36-3.36)	<0.001
ApoB (g/L)	0.55 (0.47-0.63)	0.73 (0.66-0.82)	0.92 (0.83-1.04)	<0.001
ApoA1 (g/L)	1.19 (1.06-1.32)	1.10 (0.99-1.23)	1.01 (0.91-1.13)	<0.001
ALT (U/L)	22 (15-32)	23 (16-35)	24 (16-37)	<0.001
GGT (U/L)	20 (14-31)	23 (16-34)	26 (18-42)	<0.001
TBA (μmol/L)	3.80 (2.30-5.80)	3.60 (2.28-6.10)	3.30 (2.00-5.60)	<0.001
Hcy (μmol/L)	16.00 (12.40-21.78)	16.55 (13.30-22.48)	17.50 (13.50-24.20)	<0.001
TnT-hs (ng/mL)	0.01 (0.01-0.02)	0.01 (0.01-0.06)	0.02 (0.01-0.20)	<0.001
CK-MB (U/L)	12 (8-17)	11 (8-15)	12 (9-18)	<0.001
NT-pro-BNP (pg/mL)	134.40 (63.12-371.30)	140.30 (56.42-484.70)	163.30 (55.18-549.40)	0.011
Scr (μmol/L)	62 (52-73)	63 (53-73)	64 (55-76)	<0.001
Cys C (mg/L)	0.84 (0.64-1.09)	0.84 (0.65-1.08)	0.85 (0.66-1.09)	0.820
HbA1c (%)	5.7 (5.4-6.2)	5.7 (5.4-6.2)	5.8 (5.5-6.5)	<0.001
Hs-CRP (mg/L)	0.91 (0.42-2.39)	1.35 (0.65-3.62)	2.39 (0.94-8.16)	<0.001
FIB (g/L)	2.92 (2.50-3.40)	3.04 (2.62-3.56)	3.23 (2.73-3.97)	<0.001
D-D (mg/L)	0.44 (0.30-0.60)	0.45 (0.30-0.62)	0.50 (0.31-0.70)	<0.001
AMI	221 (12.9)	395 (23.0)	602 (34.9)	<0.001
Single-vessel	711 (41.4)	596 (34.7)	545 (31.6)	<0.001
Double-vessel	513 (29.8)	562 (32.7)	506 (29.4)
Triple-vessel	495 (28.8)	560 (32.6)	673 (39.0)
Gensini	32.00 (17.00-60.00)	42.00 (21.00-71.25)	49.00 (25.00-82.00)	<0.001

Patients were divided into three ApoB/A1-L, ApoB/A1-M, and ApoB/A1-H groups based on the ApoB/A1 level. Data are presented as the medians (25th, 75th percentiles) or number (%). Age, heart rate, RDW, Hct, TC, TG, HDL, LDL, ApoB, ApoA1, ALT, GGT, TBA, Hcy, TnT-hs, CK-MB, NT-pro-BNP, Scr, Cys C, HbA1c, Hs-CRP, FIB, D-D, and Gensini score were given as medians (25th, 75th percentiles); sex, hypertension, diabetics, smoking history, AMI, single-vessel, double-vessel, and triple-vessel were given as number (%) (). TC = total cholesterol; TG = triglyceride; HDL = high-density lipoprotein cholesterol; LDL = low-density lipoprotein cholesterol; ApoB = apolipoprotein B; ApoA1 = apolipoprotein A1; ALT = alanine aminotransferase; GGT = gamma-glutamyl transpeptidase; TBA = total bile acids; Hcy = homocysteine; TnT-hs = hypersensitive troponin T; CK-MB = creatine kinase MB; NT-pro-BNP = N-terminal probrain natriuretic peptide; Scr = serum creatinine; Cys C = cystatin C; HbA1c = hemoglobin A1c; Hs-CRP = high-sensitivity C-reactive protein; FIB = fibrinogen; D-D = D-dimer; AMI = acute myocardial infarction; CAD = coronary artery disease.