Research Article

miR-29a-5p Alleviates Traumatic Brain Injury- (TBI-) Induced Permeability Disruption via Regulating NLRP3 Pathway

Figure 4

miR-29a-5p overexpression inhibited NLRP3 expression in TBI model cells. (a). miR-29a-5p overexpression reduced IL-1β and IL-18 concentration in TBI model cells. (b) miR-29a-5p enriched in TBI model cells transduced with mimic-5p. (c) The protein levels of ZO-1, occludin, NLRP3, Pro-Caspase-1, and Cleaved Caspase-1 were determined using western blot. compared with the control, !!! compared with miNC.
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