Research Article
miR-29a-5p Alleviates Traumatic Brain Injury- (TBI-) Induced Permeability Disruption via Regulating NLRP3 Pathway
Figure 6
miR-29a-5p mimic injection induced the alleviation of BBB permeability in the TBI mouse model. (a) Brain morphology was evaluated using HE staining (). Amplification of 200x. (b) The permeability of mouse BBB was analyzed using Evans blue (EB) staining assay (). (c) Cerebral water content was examined (). (d) Serum levels of IL-1 β and IL-18 were analyzed using ELISA (). (e) The protein levels of NLRP3, Pro-Caspase-1, Cleaved Caspase-1, ZO-1, and occludin were determined using western blot (). compared with the control, !!! compared with miNC.
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