Research Article

A Retrospective Cohort Study on the Association between Red Cell Distribution Width and All-Cause Mortality of Patients with Cholecystitis at ICU Admission

Table 5

Relationship between RDW and 30-day, 90-day, and 1-year mortality in different models.

NonadjustedAdjusted IAdjusted II
HR (95% CI)HR (95% CI)HR (95% CI)

30-day mortality
 RDW1.267 (1.185, 1.355)<0.0011.291 (1.207, 1.381)<0.0011.183 (1.080, 1.295)<0.001
 RDWQuintile
  12.1-13.9%111
  14.0-14.8%2.280 (0.876, 5.933)0.0912.310 (0.887, 6.014)0.0863.194 (1.107, 9.217)0.032
  14.9-15.8%3.042 (1.207, 7.663)0.0182.960 (1.171, 7.483)0.0223.390 (1.223, 9.401)0.019
  15.9-17.2%4.270 (1.745, 10.445)0.0014.465 (1.820, 10.954)0.0013.655 (1.364, 9.791)0.010
  17.3-26.9%7.277 (3.060, 17.302)<0.0018.227 (3.443, 19.659)<0.0015.328 (1.990, 14.26)0.001
 RDW for trend1.551 (1.326, 1.813)<0.0011.610 (1.371, 1.890)<0.0011.337 (1.120, 1.597)0.001
90-day mortality
 RDW1.241 (1.173, 1.313)<0.0011.266 (1.196, 1.341)<0.0011.175 (1.089, 1.268)<0.001
 RDWQuintile
  12.1-13.9%111
  14.0-14.8%2.432 (1.12, 5.282)0.0252.458 (1.131, 5.340)0.0232.411 (1.064, 5.465)0.035
  14.9-15.8%3.977 (1.907, 8.292)<0.0013.862 (1.847, 8.075)<0.0013.262 (1.503, 7.079)0.003
  15.9-17.2%4.639 (2.239, 9.614)<0.0014.900 (2.359, 10.175)<0.0013.122 (1.454, 6.703)0.004
  17.3-26.9%7.486 (3.681, 15.226)<0.0018.367 (4.099, 17.083)<0.0014.120 (1.919, 8.847)<0.001
 RDW for trend1.522 (1.345, 1.721)<0.0011.576 (1.389, 1.787)<0.0011.287 (1.123, 1.476)<0.001
1-year mortality
 RDW1.223 (1.164, 1.285)<0.0011.244 (1.184, 1.307)<0.0011.162 (1.089, 1.240)<0.001
 RDWQuintile
  12.1-13.9%111
  14.0-14.8%1.963 (1.093, 3.524)0.0241.971 (1.097, 3.539)0.0231.982 (1.081, 3.637)0.027
  14.9-15.8%3.049 (1.751, 5.311)<0.0012.910 (1.667, 5.081)<0.0012.557 (1.435, 4.556)0.001
  15.9-17.2%3.559 (2.055, 6.163)<0.0013.759 (2.165, 6.524)<0.0012.558 (1.444, 4.531)0.001
  17.3-26.9%5.492 (3.216, 9.380)<0.0016.116 (3.568, 10.484)<0.0013.208 (1.812, 5.679)<0.001
 RDW for trend1.455 (1.314, 1.611)<0.0011.505 (1.356, 1.671)<0.0011.256 (1.123, 1.404)<0.001

CI = confidence interval; HR = hazard ratio. Adjusted I for age, gender, and ethnicity. Adjusted II for age, ethnicity, time in hospital, first care unit, QSOFA, LODS, SAPSII, mean corpuscular volume, mean corpuscular hemoglobin, white blood count, red blood cell, blood urea nitrogen, hematocrit, creatinine, infection, liver disease, blood loss anemia, deficiency anemias, and weight loss. Reference group: RDW level 12.1-13.9%.