Clinical Utility of Serum Holotranscobalamin Measurements in Patients with First-Ever Ischemic Stroke
Table 3
Logistic regression analysis results for predicting ischemic stroke.
Variables
Univariable
Multivariable
coefficient (SE)
OR (95% CI)
coefficient (SE)
OR (95% CI)
holoTC (pmol/L)
-0.004 (0.002)
0.996 (0.993–0.999)
<0.01
—
—
>0.05
Total vitamin B12 (pg/mL)
-0.001 (0.001)
0.999 (0.998–1.000)
0.01
—
—
>0.05
holoTC/total vitamin B12 (%)
-0.410 (0.011)
0.960 (0.938–0.981)
<0.01
-0.450 (0.013)
0.956 (0.932–0.981)
<0.01
Homocysteine (μmol/L)
0.270 (0.049)
1.310 (1.190–1.442)
<0.01
0.251 (0.051)
1.285 (1.163–1.421)
<0.01
Hemoglobin A1c (%)
0.503 (0.133)
1.653 (1.274–2.144)
<0.01
—
—
>0.05
Fasting glucose (mg/dL)
0.014 (0.004)
1.014 (1.006–1.021)
<0.01
0.015 (0.004)
1.015 (1.007–1.024)
<0.01
Triglyceride (mg/dL)
—
—
>0.05
—
—
—
LDL cholesterol (mg/dL)
—
—
>0.05
—
—
—
Total cholesterol (mg/dL)
—
—
>0.05
—
—
—
BMI (kg/m2)
0.152 (0.042)
1.164 (1.073–1.263)
<0.01
0.118 (0.046)
1.125 (1.029–1.231)
0.01
Abbreviations: SE: standard error; CI: confidence interval; holoTC: holotranscobalamin; LDL: low-density lipoprotein; BMI: body mass index. Calculated after unifying the units for total vitamin B12 and holotranscobalamin.
