High DND1 Level Indicates a Poor Prognostic Factor in Prostate Cancer

Table 2

Clinicopathologic variables and DND1 expression in 83 prostate cancer patients.

Variable	Group	DND1 expression			value^#
			Low	High
Age	<70	55	23 (27.7%)	32 (38.6%)	0.065
	≥70	28	6 (7.2%)	22 (26.5%)
Perioperative PSA	≤10	20	9 (10.8%)	11 (13.3%)	0.279
	>10	63	20 (24.1%)	43 (51.8%)
Clinical stage	T2	22	13 (15.7%)	9 (10.8%)	0.006
	T3-4	61	16 (19.3%)	45 (54.2%)
ISUP grading group	ISUP1-2	41	27 (32.5%)	14 (16.9%)	<0.001
	ISUP3-5	42	2 (2.4%)	40 (48.2%)
Seminal vesicle invasion	Absence	12	0 (0%)	12 (14.5%)	0.006
	Presence	71	29 (34.9%)	42 (50.6%)
Lymph node metastasis	Absence	6	0 (0%)	6 (7.2%)	0.087
	Presence	77	29 (34.9%)	48 (57.8%)
Bone metastasis	Absence	6	1 (1.2%)	5 (6%)	0.596
	Presence	77	28 (33.7%)	49 (59.0%)

^# value was analyzed by the chi-square test. with statistical significance.