Research Article

Role of ssDNA as a Noninvasive Indicator for the Diagnosis and Prognosis of Hepatocellular Carcinoma: An Exploratory Study

Table 2

Comparison of ssDNA levels between different liver diseases and healthy individuals.

SubjectsNo.ssDNA (ng/μL), median (IQR)

Healthy individuals459.36 (8.01-10.90)
Cirrhosis219.64 (8.93-11.68)0.15a
Chronic hepatitis209.76 (8.52-11.28)0.39a
HCC10223.20 (16.86-44.40)<0.001b

IQR: interquartile range. aComparison with healthy individuals was analyzed using the Mann–Whitney test; bcomparison among the multiple groups was analyzed using the Kruskal-Wallis test.