Jiangzhi Ligan Decoction Inhibits GSDMD-Mediated Canonical/Noncanonical Pyroptosis Pathways and Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease

Figure 1

Rats fed with HFD for 12 weeks developed NAFLD. Next, rats were treated with 2.3, 4.6, or 9.2 g/kg JZLGD once a day for 6 weeks. (a–c) Body weight, liver weight, and liver index of NAFLD rats treated with JZLGD. (d–g) Serum TG, TC, FFA, and LDL levels as determined with a fall-automatic biochemical analyzer. (h, i) ALT and AST (enzymes related to liver injury) were detected to evaluate liver injury. Data are expressed as the (); vs. control; ^#, ^## vs. HFD group.

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