Correlation between Family RB1 Gene Pathogenic Variant with Clinical Features and Prognosis of Retinoblastoma under 5 Years Old

Table 5

RB1 gene pathogenic variants and diagnosis of age feature in 40 RB patients.

Age	N	RB1 gene pathogenic variant		Non-RB1 gene pathogenic variant
		Unilateral RB (% m/n)	Bilateral RB (% m/n)	Unilateral RB (% m/n)	Bilateral RB (% m/n)
<12 months	13	0% (0/13)	23.1% (3/13)	46.1% (6/13)	30.8% (4/13)	0.122
>12 months	27	18.5% (5/27)	40.7% (11/27)	37.0% (10/27)	3.8% (1/27)	0.003

: two patients were trilateral RB.