The Gut Microbiota and Inflammatory Factors in Pediatric Appendicitis

Figure 1

Taxonomic differences in the fecal microbiota exhibited by pediatric patients with acute appendicitis (P group) and healthy children group (Y group). A linear discriminant analysis (LDA; ) and effect size (LEfSe) analysis revealed significant differences in the fecal microbiota exhibited by P group (red, negative score) and Y group (purple, positive score). The different color nodes represent microbiota communities that are significantly enriched in the corresponding groups and significantly influence the differences between the groups; the pale yellow nodes indicate that the microbial groups either have no significant effect on the different groups or have no significant effect on the differences between groups. Linear discriminant analysis (LDA) integrated with effect size (LEfSe). (a) Cladogram indicating the phylogenetic distribution of microbiota correlated with the P or Y groups. (b) The differences in abundance between the P and Y groups.

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