Serine Protease 3 Promotes Progression of Diffuse Large B-Cell Lymphoma and Serves as a Novel Prognostic Predictor

Figure 3

Survival analyses of enrolled DLBCL patients. The overall survival of enrolled DLBCL patients was analyzed in different subgroups according to patients age (a), B symptoms (b), Ann Arbor stage (c), ECOG PS (d), serum LDH level (e), ENI (f), IPI (g), COO (h), and PRSS3 protein levels (i). Data were analyzed using Kaplan-Meier method and compared with log-rank test. Abbreviations: PRSS3: serine protease 3; DLBCL: diffuse large B-cell lymphoma; ECOG PS: Eastern Cooperative Oncology Group performance status; LDH: lactate dehydrogenase; ENI: extra nodal involvement; IPI: International Prognostic Index; COO: cell-of-origin; GCB: germinal center B cell; and ABC: activated B cell.

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