Serum Sestrin2 Was Lower in Septic Shock Patients with Cardiomyopathy

Table 4

Comparison of clinical parameters between the survival and death groups in patients with septic shock and sepsis-induced cardiomyopathy.

	SS		-value	SICM		-value
	Survival group ( = 128)	Death group ( = 60)		Survival group ( = 22)	Death group ( = 39)
Age (year)	62 [50-72]	68 [62-74]	0.002	58 [25-70]	66 [58-73]	0.029
Sex (male%)	78 (60.9%)	37 (61.7%)	0.924	11 (50%)	24 (61%)	0.382
SOFA score	12 [10-16]	14 [12-17]	0.01	10 [8-14]	14 [12-17]	0.001
APACHEII score	25 [19-31]	26 [18-32]	0.799	25 [18-29]	26 [19-34]	0.685
PCT (ng/L)	11.7 [2.7-27.9]	18.2 [2.6-46.7]	0.459	20.3 [5.4-35.5]	19 [3.9-47.1]	0.839
Lactate (mmol/L)	2.6 [2.1-3.7]	4.1 [2.9-5.2]	<0.01	3.5 [2.6-4.9]	4.9 [3.6-5.8]	0.022
Positive bacteremia	86 (67.2%)	43 (71.7%)	0.537	12 (54%)	32 (82%)	0.021
Sestrin2 (ng/mL)	14.6[9.1-19.6]	9.0[6.8-17.9]	0.014	15.1[8.7-20.9]	8.5[6.7-12.5]	0.013
Infection site			0.360			0.442
Pulmonary	37 (28.9%)	19 (31.7%)		6 (27%)	15 (38%)
Abdomen	56(43.8%)	30 (50%)		8 (36%)	17 (44%)
Urinary tract	28 (21.9%)	6 (10%)		6 (27%)	4 (10%)
Catheter elated	2(1.6%)	2 (3.3%)		1 (4%)	2 (5%)
Others	5(3.9%)	3 (5.0%)		1 (5%)	1 (3%)
SS with SICM	22 (17.2%)	39(65%)	<0.001

Note. SS: septic shock patients; SICM: sepsis-induced cardiomyopathy.