Development and Validation of a Liquid-Liquid Phase Separation-Related Gene Signature as Prognostic Biomarker for Low-Grade Gliomas

Figure 3

The development of the liquid-liquid phase separation- (LLPS-) related gene signature (GS) in the mRNAseq_693 data sets. (a) Thirteen genes were identified using the least absolute shrinkage and selection operator Cox regression analysis. (b) The time-dependent receiver operating characteristic curve (ROC) analysis. (c) The patients with high LLPS-related GS score had significantly shorter overall survival than those with low LLPS-related GS score. (d) The LLPS-related GS-based risk stratification is a prognostic factor independent of routine clinicopathological characteristics.

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