Whole Transcriptomic Analysis of Key Genes and Signaling Pathways in Endogenous ARDS

Table 2

GO and KEGG enrichment of DEGs.

Ontology	ID	Description	Gene ratio	Bg ratio	value	adjust	value
BP	GO:0032496	Response to lipopolysaccharide	67/755	499/17962	2.52e-17	1.27e-13	1.01e-13
BP	GO:0098542	Defense response to other organism	65/755	488/17962	1.16e-16	2.93e-13	2.32e-13
BP	GO:0030595	Leukocyte chemotaxis	40/755	208/17962	4.68e-16	7.87e-13	6.23e-13
BP	GO:0030593	Neutrophil chemotaxis	27/755	96/17962	1.48e-15	1.87e-12	1.48e-12
BP	GO:0019221	Cytokine-mediated signaling pathway	53/755	369/17962	3.73e-15	3.76e-12	2.98e-12
CC	GO:0034702	Ion channel complex	36/769	295/18446	7.88e-09	3.41e-06	3.04e-06
CC	GO:1902495	Transmembrane transporter complex	37/769	315/18446	1.37e-08	3.41e-06	3.04e-06
CC	GO:1990351	Transporter complex	37/769	322/18446	2.47e-08	4.08e-06	3.64e-06
CC	GO:0034703	Cation channel complex	29/769	222/18446	5.07e-08	6.29e-06	5.62e-06
CC	GO:0031012	Extracellular matrix	37/769	362/18446	4.92e-07	4.88e-05	4.36e-05
MF	GO:0005125	Cytokine activity	40/723	177/16882	2.17e-18	1.77e-15	1.56e-15
MF	GO:0008009	Chemokine activity	18/723	37/16882	1.57e-15	6.39e-13	5.62e-13
MF	GO:0030545	Receptor regulator activity	62/723	476/16882	3.92e-15	1.06e-12	9.35e-13
MF	GO:0048018	Receptor ligand activity	58/723	441/16882	2.06e-14	4.20e-12	3.69e-12
MF	GO:0005126	Cytokine receptor binding	42/723	296/16882	7.64e-12	1.24e-09	1.09e-09
KEGG	rno04060	Cytokine-cytokine receptor interaction	56/379	277/9437	1.05e-24	2.98e-22	2.49e-22
KEGG	rno04061	Viral protein interaction with cytokine and cytokine receptor	26/379	86/9437	1.70e-16	2.42e-14	2.02e-14
KEGG	rno04657	IL-17 signaling pathway	24/379	96/9437	2.77e-13	2.63e-11	2.19e-11
KEGG	rno04668	TNF signaling pathway	24/379	116/9437	2.23e-11	1.58e-09	1.32e-09
KEGG	rno04064	NF-kappa B signaling pathway	19/379	106/9437	3.42e-08	1.94e-06	1.62e-06