Injection of Matrix Metalloproteinase-9 Leads to Ventricular Remodeling

Figure 3

Light microscope changes in the myocardial structure of each group in Stage I and Stage II rats (HE staining, normal light microscope, ×100). In Stage I rats (a–d), compared with the control group, the medium- and high-dose groups showed pathological changes in myocardial ventricular remodeling, such as cell hypertrophy, disarrangement, cytoplasmic lysis, and necrosis. In contrast, the low-dose group had no significant change. The model observed pathological changes in ventricular remodeling in the Stage II rats (e–h) compared with the control group.

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