Profiles of Acetylation Regulation Genes Contribute to Malignant Progression and Have a Clinical Prognostic Impact on Liver Cancer

Figure 5

Risk signature of acetylation regulation genes. (a) Target genes correlate with worse clinical prognosis in forestplot. The HR and 95% CI are calculated by univariate Cox regression. (b, c) The optimal gene numbers and coefficients are calculated using LASSO’s multivariate Cox regression. (d) ROC shows the predictive efficiency of the risk signature in 3-year survival rates. (e) Based on the risk score, the Kaplan–Meier survival curves of 374 liver cancer patients in the high-risk and low-risk groups. (f–g) Risk score of each patient and the respective survival time. (h) The heat map of 6 genes included in the LASSO risk score model in two groups.

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