Metabolic Profiling of Serum for Osteoarthritis Biomarkers

Table 2

List of candidate biomarkers.

Name	Fold-change	value	Direction	AUC
ESI+
ɛ, ɛ, ɛ trimethyllysine	0.3427	0.0002	Down	1
Otonecine	2.2536	0.0188	Up	0.944
Tranexamic acid	0.0472	0.0431	Down	1
Triethylamine	0.668	0.0219	Down	1
Carmustine	2.8701	0.0022	Up	1
Epiguanine	0.5722	0.003	Down	0.944
Bayer e 39 soluble	6.8063	0.0173	Up	1
Etilevodopa	9.1913	0.023	Up	1
Leu-val	0.6167	0.0006	Down	1
Melatonin	7.3363	0.016	Up	0.944
1,4-naphthoquinone	2.597	0.0428	Up	0.944
Arg-asp	3.3794	0.0177	Up	0.944
Istamycin a1	1.4538	0.0165	Up	1
Deferoxamine	2.3565	0.0185	Up	0.944
Codonocarpine	1.5971	0.0196	Up	0.944
Sophoranone	2.3365	0.0478	Up	1
Anecortave	3.1962	0.0036	Up	1
Compactin	2.1724	0.0118	Up	0.944
Quinoline	0.4259	0.0316	Down	1
12‑deoxyphorbol 20-acetate 13-(2-methylbutanoate)	2.8926	0.0189	Up	1
Khellin	0.6024	0.0093	Down	0.944
Epelsiban	3.0074	0.0036	Up	1
Nevirapine	0.1551	0.047	Down	0.944
(1r,5r)-3,3,5-trimethylcyclohexyl 5-oxo-l-prolinate	6.7929	0.0362	Up	0.944
Theaspirane	0.3567	0.0397	Down	0.944
2475675	0.1698	0.0309	Down	1
Drostanolone propionate	0.1679	0.0303	Down	1
ESI-
Ascorbic acid	2.2196	0.0004	Up	1
L-(+)-valine	2.2286	0.0345	Up	1
2‑hydroxy-1,2-diphenylethyl hydrogen sulfate	1.3409	0.038	Up	1
4-carboxy-2-(tyrosylamino)butanoate	7.7855	0.0339	Up	0.944
Gentisic acid	0.3758	0.0009	Down	1
Benzoic acid	1.9018	0.038	Up	0.944
N-(5-amino-2-[(2,6-diamino-2,6-dideoxyhexopyranosyl)oxy]; -3-{[3-o-(2,6-diamino-2,6-dideoxyhexopyranosyl)-beta-d-; ribofuranosyl]oxy}-4-hydroxycyclohexyl)acetamide	1.7462	0.0136	Up	1
D-tryptophyl-d-alanyl-d-allothreonylglycyl-d-histidyl-; l-phenylalanyl-d-methioninamide	2.6554	0.0467	Up	0.944
Probucol	2.3401	0.0132	Up	1