Graph-Theory-Based Degree Centrality Combined with Machine Learning Algorithms Can Predict Response to Treatment with Antipsychotic Medications in Patients with First-Episode Schizophrenia
Table 1
Demographic characteristics and clinical measures of schizophrenia patients and healthy controls.
SZ ()
HCs ()
value
Demographic characteristics
Age (y)
16-59 ()
17-58 ()
-0.2
0.82
Gender (male/female)
21/17
21/17
0
1b
Education (y)
4-19 ()
7-20 ()
-2.7
0.01
Clinical measurements
Family history (y/n)
5/33
—
—
—
Duration (y)
0.02-8 ()
—
—
—
Treatment before (d)
0-13 ()
—
—
—
Interscan interval (m)
1-12 ()
—
—
—
Olanzapine (mg/d)
3.7-27.3 ()
PANSS baseline
Positive score
7-31 ()
—
—
—
Negative score
7-34 ()
—
—
—
General score
30-64 ()
—
—
—
Total score
63-124 ()
—
—
—
PANSS follow-up
Positive score
7-21 ()
—
—
—
Negative score
7-28 ()
—
—
—
General score
11-42 ()
—
—
—
Total score
30-110 ()
—
—
—
Data were presented as . Abbreviation: SD: standard deviation; PANSS: positive and negative syndrome scale; :-test with .