Research Article

Graph-Theory-Based Degree Centrality Combined with Machine Learning Algorithms Can Predict Response to Treatment with Antipsychotic Medications in Patients with First-Episode Schizophrenia

Table 2

The top ten brain regions that contributed mostly to the accurate classification.

Brain regionsCluster sizePeak coordinates (MNI)Discriminative weight (%)

Right putamen35412064.51
Left inferior frontal gyrus68-4827184.21
Left putamen190-21-6-94.19
Left middle occipital gyrus79-24-99-64.13
Left middle frontal gyrus114-216543.92
Left cerebellum179-51-57-483.81
Left medial frontal gyrus91-66363.78
Right middle frontal gyrus61339543.74
Left inferior temporal gyrus54-63-21-213.41
Left angular73-39-51333.41