Research Article
Identification of Novel Diagnostic Biomarkers in Prostate Adenocarcinoma Based on the Stromal-Immune Score and Analysis of the WGCNA and ceRNA Network
Table 1
GO function and KEGG pathway analysis for differently expressed genes in the IS high group vs. IS low group and SS high group vs. SS low group.
| Group | GO | KEGG | Biology function | value | Pathway | value |
| IS | Signal transduction | | Metabolic pathways | | Neutrophil degranulation | | Focal adhesion | | Immune response | | Pathways in cancer | | Innate immune response | | PI3K-Akt signaling pathway | | Oxidation-reduction process | | Cell adhesion molecules (CAMs) | |
| SS | Signal transduction | | Metabolic pathways | | Proteolysis | | Focal adhesion | | Positive regulation of transcription from RNA polymerase II promoter | 0.001 | PI3K-Akt signaling pathway | | Immune response | | Pathways in cancer | | Cell adhesion | | ECM-receptor interaction | |
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IS: immune score; SS: stroma score; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genome.
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