Disease Markers

Research Article

The Association between Serum Anion Gap and All-Cause Mortality in Cerebral Infarction Patients after Treatment with rtPA: A Retrospective Analysis

Table 1

Subgroup analysis of the relationship between AG and whole-period mortality.


Characteristic		HR (Q1, )	HR (Q2, )	for interaction

Admission				0.211
EW EMER	434	Ref	1.81 (1.23, 1.26)
Other	514	Ref	1.30 (0.86, 1.97)
Age				0.069
≤66	482	Ref	1.81 (1.24, 2.62)
>66	466	Ref	1.32 (0.86, 2.01)
AMI				0.259
No	937	Ref	0.58 (0.08, 4.14)
Yes	11	Ref	1.58 (1.19, 2.09)
BUN				0.461
≤21	462	Ref	1.29 (1.21, 2.75)
>21	486	Ref	1.75 (1.12, 2.75)
Congestive heart failure				0.160
No	620	Ref	1.56 (0.97, 2.53)
Yes	328	Ref	1.56 (1.10, 2.20)
Coronary atherosclerosis				0.761
No	666	Ref	1.54 (0.95,2.49)
Yes	282	Ref	1.54 (1.09.2.18)
Creatinine				0.696
≤0.9	502	Ref	1.59 (1.10, 2.30)
>0,9	446	Ref	1.33 (0.84, 2.11)
Diabetes				0.324
No	555	Ref	1.54 (1.01, 2.34)
Yes	393	Ref	1.54 (1.01, 2.34)
ESRD				0.931
No	883	Ref	1.69 (0.49, 5.82)
Yes	65	Ref	1.52 (1.14, 2.04)
Ethnicity				0.042
White race	584	Ref	1.57 (1.10, 2.23)
Other	364	Ref	1.56 (0.98, 2.49)
Gender				0.015
Female	474	Ref	1.44 (0.98, 2.11)
Male	474	Ref	1.68 (1.12, 2.52)
Hyperlipidemia				0.012
No	545	Ref	2.19 (1.40, 3.40)
Yes	403	Ref	1.21 (0.84, 1.75)
Hypertension				0.611
No	774	Ref	1.08 (0.55, 2.09)
Yes	174	Ref	1.70 (1.24, 2.32)
INR				0.136
≤1.25	319	Ref	1.67 (1.19, 2.35)
>1.25	319	Ref	1.61 (1.13, 2.32)
MCHC				0.181
≤32	475	Ref	1.54 (1.05, 2.27)
>32	460	Ref	1.60 (1.07, 2.40)
MCH				0.343
≤29.5	481	Ref	1.48 (0.99, 2.20)
>29.5	454	Ref	1.66 (1.12, 2.46)
Platelet				<0.001
≤247	468	Ref	2.09 (1.34, 3.27)
>247	466	Ref	1.28 (0.89, 1.84)
RBC				0.001
≤3.11	470	Ref	1.58 (1.03, 2.41)
>3.11	465	Ref	1.60 (1.11, 2.32)
RDW				0.344
≤15.7	475	Ref	1.50 (1.06, 2.12)
>15.7	460	Ref	1.78 (1.10, 2.87)
Respiratory failure				0.674
No	578	Ref	1.84 (1.22,2,78)
Yes	370	Ref	1.32 (0.90,1.94)
WBC				0.721
≤9.9	470	Ref	1.57 (1.08,2.28)
>9.9	465	Ref	1.46 (0.95,2.24)

Abbreviations: HR: hazard ratio; SD: standard deviation; AMI: acute myocardial infarction; ESRD: end-stage renal diseaseesrd; WBC: white blood cell; BUN: blood urea nitrogen; MCH: mean corpusular hemoglobin; MCHC: mean corpusular hemoglobin concentration; MCV: mean corpusular volume; RBC: red blood count; RDW: red cell distribution width; Ref: reference; Q1: quartile 1; Q2: quartile 2; Ew emer: emergency ward.