| | Variable | Healthy control () | Hyperlipidemia patients () | FHC patients () | // | |
| | Age (years) | 51 (45, 55) | | | -0.043 | 0.966 | | Gender (male/female) | 16/48 | 28/41 | 13/12 | 3.6640 | 0.056 | | BMI | 24.3 (21.7, 27.7) | | — | -1.837 | 0.066 | | HDL-C (mmol/L) | 1.42 (1.30, 1.65) | 1.31 (1.13, 1.60) | | 44.102 | <0.001 | | LDL-C (mmol/L) | | 3.38(3.10, 4.09) | | 54.454 | <0.001 | | TG (mmol/L) | 1.20 (0.80, 1.40) | 2.10 (1.60, 3.50) | | 75.824 | <0.001 | | TC (mmol/L) | | 5.35 (4.89, 6.15) | | 57.072 | <0.001 | | FPG (mmol/L) | 5.00 (4.76, 5.36) | 5.00 (4.90, 6.00) | — | -3.487 | <0.001 | | SBP (mmHg) | 120 (110, 120) | 120 (110, 130) | — | -1.766 | 0.077 | | DBP (mmHg) | 80 (70, 80) | 80 (70, 90) | — | -1.258 | 0.208 | | Squalene (μmol/L) | 2.943 (2.408, 3.698) | 3.885 (2.754, 6.180) | 5.035 (2.886, 14.184) | 12.249 | 0.002 | | Squalene/cholesterol (%) | 0.797 (0.656, 1.105) | 0.887 (0.587, 1.532) | | 39.734 | <0.001 | | Desmosterol (μmol/L) | | | | 71.156 | <0.001 | | Desmosterol/cholesterol (%) | 0.161 (0.136, 0.190) | | 0.497 (0.349, 0.796) | 52.468 | <0.001 | | Lathosterol (μmol/L) | 5.362 (4.115, 5.613) | | 14.182 (8.649, 24.603) | 48.228 | <0.001 | | Lathosterol/cholesterol (%) | | | 0.989 (0.627, 1.272) | 27.472 | <0.001 | | Campesterol (μmol/L) | 5.296 (3.894, 7.905) | 5.242 (3.491, 8.620) | 16.150 (9.532, 28.509) | 38.999 | <0.001 | | Campesterol/cholesterol (%) | 1.484 (0.993, 2.339) | 1.180 (0.871, 1.927) | 1.049 (0.768, 1.625) | 6.442 | 0.040 | | Stigmasterol (μmol/L) | 1.193 (1.088, 1.344) | | 3.709 (2.469, 5.583) | 51.190 | <0.001 | | Stigmasterol/cholesterol (%) | 0.318 (0.282, 0.387) | | 0.217 (0.165, 0.318) | 17.292 | <0.001 | | Sitosterol (μmol/L) | 7.352 (5.305, 9.383) | 8.194 (5.763, 11.956) | 19.335 (13.342, 33.245) | 42.617 | <0.001 | | Sitosterol/cholesterol (%) | 2.080 (1.481, 2.505) | 1.842 (1.548, 2.449) | 1.291 (0.938, 1.741) | 17.663 | <0.001 |
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