Research Article

[Retracted] PSMB5 Alleviates Ulcerative Colitis by Inhibiting ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis

Figure 6

PSMB5 protects against LPS-aggravated pyroptosis by inhibiting ROS-dependent NLRP3 inflammasome under LPS and NAC conditions, in siRNA-PSMB5 transfected HIEC-6 cells, (a) CCK8 analysis of cell viabiltiy, (b) LDH activity assays of the LDH release, (c and d) DCFH-DA assay of the ROS production, and (e) Western blot analysis of cleaved caspase-1 p20, pro-IL-1β, IL-1β, pro-IL-18, IL-18, NLRP3, and ASC expressions. All data are expressed as mean ± SD ( =5). and #.
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