SPTBN2 Promotes the Progression of Thyroid Cancer by Accelerating G1/S Transition and Inhibiting Apoptosis

Figure 6

Downregulation of SPTBN2 inhibited the tumorigenesis and progression of TC cell lines by arresting G1/S transition and promoting cell apoptosis. (a) Levels of CCNE2, CDK2, CDK4, Bcl-2, P21, caspase-3, cleaved-caspase3, caspase-8, cleaved-caspase8, and Bax were evaluated via WB analysis with β-actin as the loading control. (b) Quantitative results of WB analysis (normalized to β-actin). . The data are presented as the (three independent experiments).

(a)

(b)