SPTBN2 Promotes the Progression of Thyroid Cancer by Accelerating G1/S Transition and Inhibiting Apoptosis

Table 3

The association between SPTBN2 expression and clinicopathologic features in TCGA cohort.

Clinicopathologic features	High expression ()	Low expression ()		value
Gender			0.253	0.615
Female	186	181
Male	65	70
Age (years)
			0.128	0.721
≤45	116	120
>45	135	131
Multi-nodularity			0.805	0.37
Yes	118	108
No	133	143
Histological type			26.605	<0.001^a
Classical	202	149
Other types	49	102
Tumor size (mm)			18.594	<0.001^a
≥20	120	73
<20	131	178
Lymph-node metastasis			27.167	<0.001^a
Yes	140	82
No	111	169
Distant metastasis			0	1
Yes	5	4
No	246	247
Disease stage (AJCC7)			15.084	<0.001^a
I+II	147	188
III+IV	104	63

Chi-square test. ^a value < 0.05. AJCC: American Joint Committee on Cancer.